Cell Polarity: Netrin Calms an Excitable System
نویسندگان
چکیده
In a tractable model for cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards a polarity cue provided by netrin. A new study reveals that the anchor cell polarity network can break symmetry and oscillate in the absence of netrin, suggesting the presence of interlinked positive and negative feedback loops, which are common in polarity pathways.
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ورودعنوان ژورنال:
- Current Biology
دوره 24 شماره
صفحات -
تاریخ انتشار 2014